Why Saliva?

Saliva is a rich source of white blood cells, epithelial cells, buccal cells, serum proteins, cell-free DNA, RNA, bacteria and viruses.

Saliva has a number of benefits that make it easier, safer and more cost effective than blood.

Blood Drawbacks

Invasive

Medical Supervision

Refrigeration

Stability: hours

Saliva Advantages

Non-Invasive

Home Based

Temperature Range

Stability: months

Saliva’s Untapped Potential

Saliva is far more similar to blood than commonly thought.

5 billion blood tests are performed every year in the US, 80% of which could be perfomed using saliva. Most of blood’s components (e.g., white blood cells, DNA, bacteria, antibodies, etc.) are also abundantly present in saliva, but saliva has not been used for diagnostic testing by researchers and diagnostic companies because there was no practical method of collecting, preserving, and isolating these components from saliva. Until now…

The key feature of AboGen’s disruptive technology is its proprietary preservation solution. Unlike blood samples that must be quickly refrigerated and have a testing-life expectancy of just 72 hours, AboGen’s preservation solution protects saliva components at a biological half-life of up to 120 days at room temp.

Blood

White Blood Cells
Proteins
CTCs
Cell Free DNA
DNA
RNA
Bacteria
Antibody
Platelets
Red Blood Cells

Saliva

White Blood Cells
Proteins
CTCs
Cell Free DNA
DNA
RNA
Bacteria
Antibody

Abogen’s Technology

Unlike existing technologies, it preserves ALL components of saliva.

AboGen’s S3™ A Saliva Collection Kit has been independently validated at reputable academic institutions. AboGen enables researchers to use saliva instead of blood because of saliva’s ease of use (kit can be used in patient’s home, requires just a teaspoon of saliva, and preserves all components of saliva); simple logistics (transportation of the preserved sample without need for a rush service and without need for refrigeration is facilitated from the point of collection to the lab for testing); and significant cost advantage.

Potential diagnostic applications using the AboGen saliva collection kit are numerous.  For example, the S3™ A Kit, presently sold as “Research Use Only” (RUO), can potentially be used in the future for WBC monitoring, liver function testing, lung cancer monitoring, HIV rapid screening, microbiome research, and eosinophilia monitoring for conditions such as COPD. Blood is currently used for these testing purposes.

AboGen®

White Blood Cells
Proteins
CTCs
Cell Free DNA
DNA
RNA
Bacteria
Antibody

Other Technologies

DNA
RNA
Bacteria
Antibody

Want to learn about AboGen’s saliva collection kits?